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– Key Initiatives Highlight the Role of Catalytic Collaboration to Help Advance Health Equity –
– Latest HIV Research and Development Data Drive the Next Wave of Person-Centric Scientific Discovery in Treatment, Prevention and Novel Research Strategies in HIV Cure –
FOSTER CITY, Calif.--(BUSINESS WIRE)-- Gilead Sciences, Inc. (Nasdaq: GILD) today announced its upcoming contributions to the 12th International AIDS Society Conference on HIV Science (IAS 2023), taking place in Brisbane, Australia, and virtually, from July 23-26, 2023. As the leader in HIV innovation, Gilead will provide updates on its signature initiatives and key collaborations while sharing new scientific data from its research and development programs. The breadth of data presented at the meeting, along with Gilead-led symposia, reflect its innovative approach to advancing HIV prevention, treatment and cure strategies and underscore Gilead’s focus on forming partnerships with communities worldwide as part of its unequivocal commitment to help end the HIV epidemic for everyone, everywhere.
“HIV will remain a global epidemic so long as people and communities do not have access to HIV care, services and innovative and life-saving medicines due to structural and social inequalities,” said Alex Kalomparis, Senior Vice President, Public Affairs, Gilead Sciences. “At Gilead, our efforts at the global, national and local levels aim to reduce these disparities, with an emphasis on eliminating stigma and discrimination, ensuring equitable access to people-centered HIV care and services, and forging industry-leading partnerships that expand global access to our innovative and life-saving medicines. During IAS 2023, we look forward to sharing the latest from our ongoing health equity efforts and launching a new community-based initiative that seeks to change the future of the HIV epidemic.”
Advancing Efforts to Address Barriers to HIV Care and Prevention
At IAS 2023, Gilead will convene two symposia to discuss the latest progress in policies and practical solutions from around the world to help achieve more equitable access to HIV care and services.
Ignite change: Championing HIV status-neutral care together (July 23, 3:00pm AEST), will feature an international multidisciplinary expert panel exploring how a status-neutral approach can improve care and help eliminate structural stigma; discuss steps to close the gaps in the care continuum; and consider what long-term success means for people living with HIV.
A second symposium, titled The Fire Within Us: Driven by Our Collective Passion to End the HIV Epidemic (July 24, 8:00am AEST), will highlight ongoing programs working to integrate patient-centered approaches across the HIV care continuum to improve access and care. The discussion will feature insights from a diverse panel on practical, person-centered solutions, which aim to enhance healthcare for everyone affected by HIV.
RADIAN®, a collaboration between Gilead and the Elton John AIDS Foundation, is hosting the forum; Eastern Europe and Central Asia in Crisis: Community-led strategies to leave no one behind and end the rapidly growing HIV epidemic taking place on July 24 at 6:30 p.m. AEST.
To learn more about Gilead’s unique collaborations around the world and the work to help end the HIV epidemic for everyone, everywhere, visit: https://www.gileadhivtogether.com.
Driving Transformational Innovation in HIV Research
Gilead is committed to continuous scientific discovery to meet the evolving needs of people affected by HIV. At IAS 2023, Gilead will share new findings on HIV treatment and prevention strategies, as well as the latest updates from the company’s continued pursuit of an HIV cure.
“At Gilead, our person-centered approach to developing novel medicines aims to generate findings that are meaningful and beneficial to the people and communities confronting the day-to-day realities of HIV,” said Jared Baeten, MD, PhD, Vice President, HIV Clinical Development, Gilead Sciences. “Collaboration with researchers and community stakeholders, particularly those living with HIV or those who could benefit from PrEP, is integral to all aspects of Gilead’s scientific discovery process and is essential to realizing the transformative potential impact of our innovations. IAS 2023 is an invaluable opportunity to interact directly with the broad HIV community and help further our HIV research and development efforts.”
As part of the company’s ongoing effort to advance treatment research in communities with diverse health needs, Gilead will present results from studies evaluating Biktarvy® (bictegravir 50 mg/emtricitabine 200 mg/tenofovir alafenamide 25 mg tablets, B/F/TAF) in women with HIV who are pregnant and virologically suppressed and TAF-containing regimens in virologically suppressed children with HIV. Additional presentations from Gilead’s HIV treatment research program will include new 96-week findings from ALLIANCE, an ongoing Phase III trial evaluating the efficacy and safety profile of Biktarvy versus dolutegravir 50 mg (DTG) + emtricitabine 200 mg/tenofovir disoproxil fumarate 300 mg, F/TDF, DTG+F/TDF, in adults with HIV/HBV co-infection initiating treatment.
Additionally, outcomes from multiple studies evaluating lenacapavir, Gilead’s first-in-class, long-acting HIV-1 capsid inhibitor will be presented. The latest findings will highlight patient-reported outcomes from CAPELLA, which is an ongoing Phase 2/3 registrational study designed to evaluate the antiviral activity of twice-yearly lenacapavir administered as a subcutaneous injection in heavily treatment-experienced people with multi-drug resistant HIV-1 infection. Research will also be presented on the efficacy and safety profile of temporary oral bridging with lenacapavir when the administration of subcutaneous lenacapavir was interrupted.
Insights from Gilead’s cure research program include new data evaluating broadly neutralizing antibodies and the maintenance of virologic control in the absence of antiretroviral therapy.
Gilead scientists will also contribute to three IAS-hosted satellite sessions to further advance scientific dialogue on key issues including:
Summary of Presentations
Key abstracts will include:
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| HIV Treatment Research |
OAB0104 |
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| Pharmacokinetics, safety, and efficacy of bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) in virologically suppressed pregnant women with HIV |
LBEPB13 |
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| Week-96 results of ALLIANCE, a Phase 3, randomized, double-blind study comparing bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) versus dolutegravir + emtricitabine/tenofovir disoproxil fumarate (DTG+F/TDF) in treatment-naïve people with both HIV-1 and hepatitis B |
EPA0002 |
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| Preexisting and postbaseline resistance analyses in pooled pediatric studies of emtricitabine/tenofovir alafenamide (F/TAF)-based antiretroviral therapy (ART) |
EPB0235 |
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| Weight change and metabolic assessment of virologically suppressed children with HIV aged ≥2 years and weighing 14 to |
