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Leigh Ann Pusey Lilly Corporate Center Indianapolis, Indiana 46285 Securities and Exchange Commission Washington, D.C. 20549 Authorization Regarding Reporting Forms I hereby authorize and designate the following persons to sign and file with the Commission on my behalf Forms 3, 4, and 5 (including any amendments thereto) covering my transactions and holdings in the common stock and other equity securities of Eli Lilly and Company (the "Company") as required by Section 16 of the Securities Exchange Act of 1934 and the rules thereunder: Anat Hakim, Lilly Corporate Center, Indianapolis, Indiana Christopher Anderson, Lilly Corporate Center, Indianapolis, Indiana Jonathan Groff, Lilly Corporate Center, Indianapolis, Indiana Valorie Wanner, Lilly Corporate Center, Indianapolis, Indiana This authorization and designation revoke all prior authorizations and designations relating to reporting under Section 16 of the Securities Exchange Act of 1934 of the Company's securities and shall remain in effect until revoked by a subsequently filed instrument. Date: February 22, 2022 /s/ Leigh Ann Pusey
