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Exhibit 99.1

BRISTOL-MYERS SQUIBB COMPANY
EARNINGS FROM OPERATIONS
(Unaudited, dollars and shares in millions except per share data)

 
  
2020
    
2021
  
 
  
Year
    
1st Qtr
    
2nd Qtr
    
3rd Qtr
    
4th Qtr
    
Year
  
Net product sales
  
$
41,321
    
$
10,798
    
$
11,405
    
$
11,243
    
$
11,609
    
$
45,055
  
Alliance and other revenues
    
1,197
      
275
      
298
      
381
      
376
      
1,330
  
Total Revenues
    
42,518
      
11,073
      
11,703
      
11,624
      
11,985
      
46,385
  
 
                                                
Cost of products sold(a)
    
11,773
      
2,841
      
2,452
      
2,291
      
2,356
      
9,940
  
Marketing, selling and administrative
    
7,661
      
1,666
      
1,882
      
1,788
      
2,354
      
7,690
  
Research and development(b)
    
10,048
      
2,219
      
2,478
      
2,980
      
2,518
      
10,195
  
Acquired IPRD(b)
    
12,533
      
6
      
793
      
271
      
89
      
1,159
  
Amortization of acquired intangible assets
    
9,688
      
2,513
      
2,547
      
2,546
      
2,417
      
10,023
  
Other (income)/expense, net
    
(2,314
)
    
(702
)
    
(2
)
    
(409
)
    
393
      
(720
)
Total Expenses
    
49,389
      
8,543
      
10,150
      
9,467
      
10,127
      
38,287
  
 
                                                
Earnings Before Income Taxes
    
(6,871
)
    
2,530
      
1,553
      
2,157
      
1,858
      
8,098
  
Provision for Income Taxes
    
2,124
      
501
      
492
      
605
      
(514
)
    
1,084
  
 
                                                
Net Earnings
    
(8,995
)
    
2,029
      
1,061
      
1,552
      
2,372
      
7,014
  
Noncontrolling Interest
    
20
      
8
      
6
      
6
       —      
20
  
Net Earnings Attributable to BMS
  
$
(9,015
)
  
$
2,021
    
$
1,055
    
$
1,546
    
$
2,372
    
$
6,994
  
 
                                                
Diluted Earnings/(Loss) per Common Share*
  
$
(3.99
)
  
$
0.89
    
$
0.47
    
$
0.69
    
$
1.07
    
$
3.12
  
 
                                                
Weighted-Average Common Shares Outstanding - Diluted
    
2,258
      
2,265
      
2,252
      
2,243
      
2,219
      
2,245
  

* Quarterly amounts may not add to the year-to-date amounts, as each period is computed on a discrete basis.
(a) Excludes amortization of acquired intangible assets.
(b) Research and development charges resulting from upfront or contingent milestone payments in connection with asset acquisitions or licensing of third-party intellectual property rights have been reclassified to the Acquired IPRD line item beginning with the first quarter of 2022. Prior period results have been revised for comparability.

BRISTOL-MYERS SQUIBB COMPANY
RECONCILIATION TO PREVIOUSLY REPORTED DILUTED EPS - NON-GAAP
(Unaudited, dollars and shares in millions except per share data)

 
  
2020
    
2021
  
 
  
Year
    
1st Qtr
    
2nd Qtr
    
3rd Qtr
    
4th Qtr
    
Year
  
Up-front and milestone charges previously specified
  
$
12,441
    
$
 —    
$
780
    
$
200
    
$
 —    
$
980
  
Licensing income previously specified
    
(168
)
    
(14
)
    
(15
)
     —      
(43
)
    
(72
)
Decrease/(Increase) in Earnings before income taxes - Non-GAAP
    
12,273
      
(14
)
    
765
      
200
      
(43
)
    
908
  
Income tax impact
    
(90
)
    
3
      
(96
)
    
(46
)
    
10
      
(129
)
Decrease/(Increase) in Net earnings attributable to BMS - Non-GAAP
    
12,183
      
(11
)
    
669
      
154
      
(33
)
    
779
  
 
                                                
Decrease/(Increase) in Diluted Earnings Per Share - Non-GAAP
    
5.31
      
—
   
0.30
      
0.07
      
(0.01
)
    
0.35
  
Diluted Earnings Per Share - Non-GAAP previously reported
    
6.44
      
1.74
      
1.93
      
2.00
      
1.83
      
7.51
  
Revised Diluted Earnings Per Share - Non-GAAP
    
1.13
      
1.74
      
1.63
      
1.93
      
1.84
      
7.16
  

BRISTOL-MYERS SQUIBB COMPANY
SPECIFIED ITEMS
(Unaudited, dollars in millions)

 
  
2020(a)
    
2021(a)
  
 
  
Year
    
1st Qtr
    
2nd Qtr
    
3rd Qtr
    
4th Qtr
    
Year
  
Inventory purchase price accounting adjustments
  
$
2,688
    
$
79
    
$
88
    
$
97
    
$
 —    
$
264
  
Intangible asset impairment
    
575
      
315
      
—
      
—
      
—
      
315
  
Employee compensation charges
    
4
      
—
      
—
      
—
      
—
      
—
  
Site exit and other costs
    
33
      
23
      
1
      
—
      
—
      
24
  
Cost of products sold
    
3,300
      
417
      
89
      
97
      
—
      
603
  
 
                                                
Employee compensation charges
    
275
      
—
      
1
      
—
      
—
      
1
  
Site exit and other costs
    
4
      
(1
)
    
—
      
1
      
2
      
2
  
Marketing, selling and administrative
    
279
      
(1
)
    
1
      
1
      
2
      
3
  
 
                                                
IPRD impairments
    
470
      
—
      
230
      
610
      
—
      
840
  
Inventory purchase price accounting adjustments
    
36
      
—
      
—
      
1
      
—
      
1
  
Employee compensation charges
    
282
      
1
      
—
      
—
      
—
      
1
  
Site exit and other costs
    
115
      
—
      
—
      
1
      
—
      
1
  
Research and development
    
903
      
1
      
230
      
612
      
—
      
843
  
 
                                                
Amortization of acquired intangible assets
    
9,688
      
2,513
      
2,547
      
2,546
      
2,417
      
10,023
  
 
                                                
Interest expense(b)
    
(159
)
    
(34
)
    
(28
)
    
(29
)
    
(29
)
    
(120
)
Contingent consideration
    
(1,757
)
    
(510
)
    
—
      
—
      
(32
)
    
(542
)
Equity investment (gains)/losses
    
(1,156
)
    
(608
)
    
(154
)
    
(465
)
    
469
      
(758
)
Integration expenses
    
717
      
141
      
152
      
141
      
130
      
564
  
Provision for restructuring
    
530
      
45
      
78
      
27
      
19
      
169
  
Litigation and other settlements
    
(239
)
    
—
      
—
      
—
      
—
      
—
  
Reversion excise tax
    
76
      
—
      
—
      
—
      
—
      
—
  
Divestiture (gains)/losses
    
(55
)
    
—
      
(11
)
    
2
      
—
      
(9
)
Loss on debt redemption
    
—
      
281
      
—
      
—
      
—
      
281
  
Other (income)/expense, net
    
(2,043
)
    
(685
)
    
37
      
(324
)
    
557
      
(415
)
 
                                                
Increase to pretax income
    
12,127
      
2,245
      
2,904
      
2,932
      
2,976
      
11,057
  
 
                                                
Income taxes on items above
    
(1,643
)
    
(303
)
    
(292
)
    
(137
)
    
(261
)
    
(993
)
Income taxes attributed to Otezla divestiture
    
266
      
—
      
—
      
—
      
—
      
—
  
Income taxes attributed to internal transfer of intangible assets
    
853
      
—
      
—
      
—
      
(983
)
    
(983
)
Income taxes
    
(524
)
    
(303
)
    
(292
)
    
(137
)
    
(1,244
)
    
(1,976
)
 
                                                
Increase to net earnings
  
$
11,603
    
$
1,942
    
$
2,612
    
$
2,795
    
$
1,732
    
$
9,081
  
 
(a)
Revised to exclude significant R&D charges or other income resulting from up-front and contingent milestone payments in connection with asset acquisitions or licensing of third-party intellectual property rights (including related income tax impacts).
(b)
Includes amortization of purchase price adjustments to Celgene debt.

BRISTOL-MYERS SQUIBB COMPANY
RECONCILIATION OF CERTAIN GAAP LINE ITEMS TO CERTAIN NON-GAAP LINE ITEMS
(Unaudited, dollars in millions)

 
  
2020
    
2021
  
 
  
Year
    
1st Qtr
    
2nd Qtr
    
3rd Qtr
    
4th Qtr
    
Year
  
Gross profit
  
$
30,745
    
$
8,232
    
$
9,251
    
$
9,333
    
$
9,629
    
$
36,445
  
Specified items (a)
    
3,300
      
417
      
89
      
97
      
—
      
603
  
Gross profit excluding specified items
    
34,045
      
8,649
      
9,340
      
9,430
      
9,629
      
37,048
  
 
                                                
Marketing, selling and administrative
    
7,661
      
1,666
      
1,882
      
1,788
      
2,354
      
7,690
  
Specified items (a)
    
(279
)
    
1
      
(1
)
    
(1
)
    
(2
)
    
(3
)
Marketing, selling and administrative excluding specified items
    
7,382
      
1,667
      
1,881
      
1,787
      
2,352
      
7,687
  
 
                                                
Research and development
    
10,048
      
2,219
      
2,478
      
2,980
      
2,518
      
10,195
  
Specified items (a)
    
(903
)
    
(1
)
    
(230
)
    
(612
)
    
—
      
(843
)
Research and development excluding specified items
    
9,145
      
2,218
      
2,248
      
2,368
      
2,518
      
9,352
  
 
                                                
Amortization of acquired intangible assets
    
9,688
      
2,513
      
2,547
      
2,546
      
2,417
      
10,023
  
Specified items (a)
    
(9,688
)
    
(2,513
)
    
(2,547
)
    
(2,546
)
    
(2,417
)
    
(10,023
)
Amortization of acquired intangible assets excluding specified items
    
—
      
—
      
—
      
—
      
—
      
—
  
 
                                                
Other (income)/expense, net
    
(2,314
)
    
(702
)
    
(2
)
    
(409
)
    
393
      
(720
)
Specified items (a)
    
2,043
      
685
      
(37
)
    
324
      
(557
)
    
415
  
Other (income)/expense, net excluding specified items
    
(271
)
    
(17
)
    
(39
)
    
(85
)
    
(164
)
    
(305
)
 
                                                
Earnings/(Loss) before income taxes
    
(6,871
)
    
2,530
      
1,553
      
2,157
      
1,858
      
8,098
  
Specified items(a)
    
12,127
      
2,245
      
2,904
      
2,932
      
2,976
      
11,057
  
Earnings before income taxes excluding specified items
    
5,256
      
4,775
      
4,457
      
5,089
      
4,834
      
19,155
  
 
                                                
Provision/(benefit) for income taxes
    
2,124
      
501
      
492
      
605
      
(514
)
    
1,084
  
Income taxes on specified items(a)
    
1,643
      
303
      
292
      
137
      
261
      
993
  
Income taxes attributed to Otezla® divestiture(a)
    
(266
)
    
—
      
—
      
—
      
—
      
—
  
Income taxes attributed to internal transfer of intangible assets(a)
    
(853
)
    
—
      
—
      
—
      
983
      
983
  
Provision for income taxes excluding tax on specified items and income taxes attributed to Otezla® divestiture and internal transfer of intangible assets
    
2,648
      
804
      
784
      
742
      
730
      
3,060
  
 
                                                
Noncontrolling Interest
    
20
      
8
      
6
      
6
      
—
      
20
  
Specified items(a)
    
—
      
—
      
—
      
—
      
—
      
—
  
Noncontrolling Interest excluding specified items
    
20
      
8
      
6
      
6
      
—
      
20
  
 
                                                
Net Earnings/(Loss) attributable to BMS used for Diluted EPS Calculation - GAAP
    
(9,015
)
    
2,021
      
1,055
      
1,546
      
2,372
      
6,994
  
Specified items(a)
    
11,603
      
1,942
      
2,612
      
2,795
      
1,732
      
9,081
  
Net earnings attributable to BMS used for Diluted EPS Calculation excluding specified items - Non-GAAP
    
2,588
      
3,963
      
3,667
      
4,341
      
4,104
      
16,075
  
 
                                                
Weighted-average Common Shares Outstanding - Diluted - GAAP
    
2,258
      
2,265
      
2,252
      
2,243
      
2,219
      
2,245
  
Weighted-average Common Shares Outstanding - Diluted - Non-GAAP
    
2,293
      
2,265
      
2,252
      
2,243
      
2,219
      
2,245
  
 
                                                
Diluted Earnings/(Loss) Per Share - GAAP*
  
$
(3.99
)
  
$
0.89
    
$
0.47
    
$
0.69
    
$
1.07
    
$
3.12
  
Diluted Earnings Per Share attributable to specified items(a)
    
5.12
      
0.85
      
1.16
      
1.24
      
0.77
      
4.04
  
Diluted Earnings Per Share - Non-GAAP*
  
$
1.13
    
$
1.74
    
$
1.63
    
$
1.93
    
$
1.84
    
$
7.16
  
 
                                                
Effective Tax Rate
    
(30.9
)%
    
19.8
%
    
31.7
%
    
28.0
%
    
(27.7
)%
    
13.4
%
Specified items(a)
    
81.3
%
    
(3.0
)%
    
(14.1
)%
    
(13.5
)%
    
42.8
%
    
2.6
%
Effective Tax Rate excluding specified items
    
50.4
%
    
16.8
%
    
17.6
%
    
14.6
%
    
15.1
%
    
16.0
%

*
Quarterly amounts may not add to the year-to-date amounts, as each period is computed on a discrete basis.
(a)
Refer to the Specified Items schedule for further details. Effective tax rate on the Specified Items represents the difference between the GAAP and Non-GAAP effective tax rate.

BRISTOL-MYERS SQUIBB COMPANY
USE OF NON-GAAP FINANCIAL INFORMATION

In discussing financial results, the Company refers to financial measures that are not in accordance with U.S. Generally Accepted Accounting Principles (GAAP). These non-GAAP financial measures, provided as supplemental information to the financial measures presented in this exhibit that are calculated and presented in accordance with GAAP, are presented because management has evaluated the Company’s financial results both including and excluding the adjusted items or the effects of foreign currency translation, as applicable, and believes that the non-GAAP financial measures presented supplement or enhance management, analysts and investors overall understanding of the Company’s underlying financial performance and trends and facilitate comparisons among current, past and future periods.

Non-GAAP financial measures such as non-GAAP earnings and related EPS information are adjusted to exclude certain costs, expenses, gains and losses and other specified items that are evaluated on an individual basis after considering their quantitative and qualitative aspects and typically have one or more of the following characteristics, such as being highly variable, difficult to project, unusual in nature, significant to the results of a particular period or not indicative of past or future operating results. These items are excluded from non-GAAP earnings and related EPS information because the Company believes they neither relate to the ordinary course of the Company’s business nor reflect the Company’s underlying business performance. Similar charges or gains were recognized in prior periods and will likely reoccur in future periods, including amortization of acquired intangible assets, including product rights that generate a significant portion of our ongoing revenue and will recur until the intangible assets are fully amortized, unwind of inventory purchase price adjustments, acquisition and integration expenses, restructuring costs, accelerated depreciation and impairment of property, plant and equipment and intangible assets, divestiture gains or losses, stock compensation resulting from accelerated vesting of Celgene awards, certain retention-related employee compensation charges related to the Celgene transaction, pension, legal and other contractual settlement charges, equity investment and contingent value rights fair value adjustments (including fair value adjustments attributed to limited partnership equity method investments beginning in 2021) and amortization of fair value adjustments of debt acquired from Celgene in our 2019 exchange offer, among other items. Certain other significant tax items are also excluded such as the impact resulting from internal transfers due to streamlining our legal entity structure subsequent to the Celgene acquisition and the global intangible low taxed income tax change upon finalization of the Otezla* divestiture in 2020. Deferred and current income taxes attributed to these items are also adjusted for considering their individual impact to the overall tax expense, deductibility and jurisdictional tax rates. The Company will modify its presentation of non-GAAP results and no longer exclude from non-GAAP results significant R&D charges or other income resulting from upfront or contingent milestone payments in connection with asset acquisitions or licensing of third-party intellectual property rights beginning in the first quarter of 2022. For the purposes of comparability with future periods, the non-GAAP financial measures for the year ended December 31, 2020, each of the four quarters of 2021 and the year ended December 31, 2021, presented in this exhibit have been updated to reflect this change; however, the Company has reconciled non-GAAP diluted earnings per share as calculated using the new methodology to the previously reported non-GAAP diluted earnings per share to allow investors and readers to evaluate this non-GAAP measure using the historic methodologies in place as of the applicable dates.

Because the non-GAAP financial measures are not calculated in accordance with GAAP, they should not be considered superior to and are not intended to be considered in isolation or as a substitute for the related financial measures presented in this exhibit that are prepared in accordance with GAAP and may not be the same as or comparable to similarly titled measures presented by other companies due to possible differences in method and in the items being adjusted. We encourage investors to review our financial statements and publicly-filed reports in their entirety and not to rely on any single financial measure.

Reconciliations of the non-GAAP financial measures to the most comparable GAAP measures are provided in the accompanying financial tables. Within the accompanying financial tables presented, certain columns and rows may not add due to the use of rounded numbers. Percentages and earnings per share amounts presented are calculated from the underlying amounts.