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INDIANAPOLIS, March 9, 2021 /PRNewswire/ -- New data from 10 studies will be presented by Eli Lilly and Company (NYSE: LLY) at the upcoming virtual International Conference on Alzheimer's & Parkinson Diseases™ 2021 (AD/PD™ 2021), March 9-14, 2021. Lilly will present detailed results of the TRAILBLAZER-ALZ phase 2 study, which showed that donanemab treatment resulted in significant slowing of decline in a composite measure of cognition and daily function in people with early symptomatic Alzheimer's disease (AD) compared to placebo. Additional data highlight Lilly's AD program focused on developing both disease-modifying therapies that slow clinical progression by targeting the underlying causes of AD and novel diagnostics and biomarkers to enable a timely and more accurate diagnosis.
"These data bring us hope that we are closer to finding solutions for people and their families suffering from this devastating disease," said Mark Mintun, M.D., vice president of Alzheimer's disease development unit, Eli Lilly and Company. "We are proud of our research findings and encouraged by the possibility to accelerate the diagnosis of Alzheimer's disease and the development of innovative treatments to stop it."
For over 30 years, Lilly has been committed to bringing innovative AD therapies and diagnostics to patients and continues to lead the research field. Lilly's neurodegeneration pipeline reflects innovation, investments and collaborations aimed at the entire spectrum of AD, including disease-modifying therapies that target the underlying causes of the disease, symptomatic therapies, and imaging and blood biomarkers to support earlier detection.
The breadth of data being presented at the meeting reflects Lilly's expertise in blood-based screening and amyloid and tau imaging. These diagnostic strategies are also integrated into Lilly's robust approach to AD clinical trials including the TRAILBLAZER-ALZ trials. Studies being presented include (please note, times listed below are Central European Time (CET) as virtual conference will be hosted from Barcelona and may be subject to change):
Donanemab
Blood Biomarker Data
Public/Private Collaborations
Mevidalen/D1PAMs
About Alzheimer's DiseaseAlzheimer's disease is a fatal illness that causes progressive decline in memory and other aspects of cognition. Dementia due to Alzheimer's disease is the most common form of dementia, accounting for 60 to 80 percent of all cases1. There are currently over 50 million people living with dementia around the world, with numbers expected to increase to nearly 152 million by 20502. Almost 10 million new cases of dementia are diagnosed each year worldwide, implying one new case every 3 seconds, and a significant increase in the caregiving burden placed on society and families. In the US alone, there was an increase of 8 million new caregivers from 2015 to 20203. The current annual societal and economic cost of dementia is estimated at $1 trillion, an amount that is expected to double by 2030 unless we find a way to slow the disease.
About Avid Radiopharmaceuticals The mission of Avid Radiopharmaceuticals, a wholly owned subsidiary of Lilly, is to discover and develop radiopharmaceuticals and imaging methods that improve global health by accelerating the development of new medicines and enabling a tailored approach to healthcare.
About Eli Lilly and CompanyLilly is a global health care leader that unites caring with discovery to create medicines that make life better for people around the world. We were founded more than a century ago by a man committed to creating high-quality medicines that meet real needs, and today we remain true to that mission in all our work. Across the globe, Lilly employees work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to communities through philanthropy and volunteerism. To learn more about Lilly, please visit us at lilly.com and lilly.com/newsroom. P-LLY
Lilly Cautionary Statement Regarding Forward-Looking Statements
This press release contains forward-looking statements (as that term is defined in the Private Securities Litigation Reform Act of 1995) about donanemab as a potential treatment for people with early symptomatic Alzheimer's disease and reflects Lilly's current beliefs and expectations. However, as with any such undertaking, there are substantial risks and uncertainties in the process of drug research, development, and commercialization. Among other things, there is no guarantee that future study results will be consistent with study results to date, that donanemab will prove to be a safe and effective treatment, or that donanemab will receive regulatory approval. For further discussion of these and other risks and uncertainties, see Lilly's Form 10-K and Form 10-Q filings with the United States Securities and Exchange Commission. Except as required by law, Lilly undertakes no duty to update forward-looking statements to reflect events after the date of this release.
1 https://www.alz.org/alzheimers-dementia/facts-figures 2 https://www.alz.co.uk/research/WorldAlzheimerReport2019.pdf 3 https://www.aarp.org/content/dam/aarp/ppi/2020/05/full-report-caregiving-in-the-united-states.doi.10.26419-2Fppi.00103.001.pdf
Refer to: | Gina Goodenough; demayo_gina_maria@lilly.com; 646-221-3022 – Media |
Kevin Hern; hern_kevin_r@lilly.com; 317-277-1838 – Investor Relations |
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SOURCE Eli Lilly and Company
