ASPEN PHARMACARE HOLDINGS LIMITED (Incorporated in the Republic of South Africa) Registration number: 1985/002935/06 Share code: APN ISIN: ZAE000066692 LEI: 635400ZYSN1IRD5QWQ94 DEALING IN SECURITIES BY DIRECTORS, PRESCRIBED OFFICERS AND THE COMPANY SECRETARY OF THE COMPANY In compliance with paragraph 3.63 of the Listings Requirements of the JSE Limited, disclosure is made of the following information: DIRECTORS OF THE COMPANY Director : Stephen Bradley Saad Date of transaction : 14 September 2022 Nature of transaction : Acceptance of deferred incentive bonus shares (vesting after three years) Number of securities : 50 310 Class of securities : Ordinary shares Grant price : R142.7808 Value of Transaction : R7 183 302.05 Nature of interest : Direct beneficial Clearance obtained : Yes Director : Sean Matthew Capazorio Date of transaction : 14 September 2022 Nature of transaction : Acceptance of deferred incentive bonus shares (vesting after three years) Number of securities : 22 851 Class of securities : Ordinary shares Grant price : R142.7808 Value of Transaction : R3 262 684.06 Nature of interest : Direct beneficial Clearance obtained : Yes PRESCRIBED OFFICERS OF THE COMPANY Prescribed Officer : Michael Guy Attridge Date of transaction : 14 September 2022 Nature of transaction : Acceptance of deferred incentive bonus shares (vesting after three years) Number of securities : 41 590 Class of securities : Ordinary shares Grant price : R142.7808 Value of Transaction : R5 938 253.47 Nature of interest : Direct beneficial Clearance obtained : Yes Prescribed Officer : Reginald Haman Date of transaction : 14 September 2022 Nature of transaction : Acceptance of deferred incentive bonus shares (vesting after three years) Number of securities : 17 498 Class of securities : Ordinary shares Grant price : R142.7808 Value of Transaction : R2 498 378.44 Nature of interest : Direct beneficial Clearance obtained : Yes Prescribed Officer : Reginald Haman Date of transaction : 14 September 2022 Nature of transaction : Acceptance of deferred retention bonus shares (vesting after three, five and 7 years in tranches of 24 000, 32 000 and 44 000 shares, respectively) Number of securities : 100 000 Class of securities : Ordinary shares Grant price : R142.7808 Value of Transaction : R14 278 080.00 Nature of interest : Direct beneficial Clearance obtained : Yes Prescribed Officer : Lorraine Angela Hill Date of transaction : 14 September 2022 Nature of transaction : Acceptance of deferred incentive bonus shares (vesting after three years) Number of securities : 18 215 Class of securities : Ordinary shares Grant price : R142.7808 Value of Transaction : R2 600 752.27 Nature of interest : Direct beneficial Clearance obtained : Yes Prescribed Officer : Zizipho Mmango Date of transaction : 14 September 2022 Nature of transaction : Acceptance of deferred incentive bonus shares (vesting after three years) Number of securities : 17 498 Class of securities : Ordinary shares Grant price : R142.7808 Value of Transaction : R2 498 378.44 Nature of interest : Direct beneficial Clearance obtained : Yes Prescribed Officer : Zizipho Mmango Date of transaction : 14 September 2022 Nature of transaction : Acceptance of deferred retention bonus shares (vesting after three, five and 7 years in tranches of 24 000, 32 000 and 44 000 shares, respectively) Number of securities : 100 000 Class of securities : Ordinary shares Grant price : R142.7808 Value of Transaction : R14 278 080.00 Nature of interest : Direct beneficial Clearance obtained : Yes Prescribed Officer : Mark Sardi Date of transaction : 14 September 2022 Nature of transaction : Acceptance of deferred incentive bonus shares (vesting after three years) Number of securities : 17 498 Class of securities : Ordinary shares Grant price : R142.7808 Value of Transaction : R2 498 378.44 Nature of interest : Direct beneficial Clearance obtained : Yes COMPANY SECRETARY OF THE COMPANY Company Secretary : Riaan Verster Date of transaction : 14 September 2022 Nature of transaction : Acceptance of deferred incentive bonus shares (vesting after three years) Number of securities : 7 558 Class of securities : Ordinary shares Grant price : R142.7808 Value of Transaction : R1 079 137.29 Nature of interest : Direct beneficial Clearance obtained : Yes All acceptances of deferred bonus shares are deemed to be off-market trades. Durban 15 September 2022 Sponsor Investec Bank Limited