ASPEN PHARMACARE HOLDINGS LIMITED (Incorporated in the Republic of South Africa) (“Aspen Holdings”) Registration number: 1985/002935/06 Share code: APN ISIN: ZAE000066692 LEI: 635400ZYSN1IRD5QWQ94 (“Aspen” or “the Company”) DEALING IN ASPEN SECURITIES In compliance with the JSE Limited Listings Requirements, shareholders are advised of the following dealings in Aspen’s securities by a third party intermediary (“the Intermediary”). A hedging transaction was entered into with the Intermediary to enable the Company to settle its future obligation to employees participating in the SA Management Deferred Incentive Bonus Scheme (“the Scheme”) of Aspen Holdings and three of its wholly owned South African subsidiaries, namely Pharmacare Limited, Aspen Finance (Pty) Limited and Aspen SA Operations (Pty) Limited. In terms of this hedging transaction the Intermediary acquired Aspen shares as follows: Date of transaction: 14 October 2022 Nature and details of transaction On-market purchase of securities to satisfy the future by intermediary: obligations towards participants of the Scheme Number of securities: 283 025 Purchase price: R146.1614 Total value of the transaction: R41 367 330.24 Class of securities: Ordinary Shares Nature of interest: Direct beneficial Clearance obtained: Yes Date of transaction: 17 October 2022 Nature and details of transaction On-market purchase of securities to satisfy the future by intermediary: obligations towards participants of the Scheme Number of securities: 242 367 Purchase price: R150.1206 Total value of the transaction: R36 384 279.46 Class of securities: Ordinary Shares Nature of interest: Direct beneficial Clearance obtained: Yes Date of transaction: 17 October 2022 Nature and details of transaction On-market purchase of securities to satisfy the future by intermediary: obligations towards participants of the Scheme Number of securities: 145 369 Purchase price: R151.5817 Total value of the transaction: R22 035 280.15 Class of securities: Ordinary Shares Nature of interest: Direct beneficial Clearance obtained: Yes Date of transaction: 19 October 2022 Nature and details of transaction On-market purchase of securities to satisfy the future by intermediary: obligations towards participants of the Scheme Number of securities: 203 682 Purchase price: R151.2235 Total value of the transaction: R30 801 514.93 Class of securities: Ordinary Shares Nature of interest: Direct beneficial Clearance obtained: Yes Durban 21 October 2022 Sponsor: Investec Bank Limited