ASPEN PHARMACARE HOLDINGS LIMITED (Incorporated in the Republic of South Africa) (“Aspen Holdings” or “Company”) Registration number: 1985/002935/06 Share code: APN ISIN: ZAE000066692 LEI: 635400ZYSN1IRD5QWQ94 and its subsidiaries (collectively “Aspen” or “the Group”) NOTIFICATION IN TERMS OF SECTION 122(3) OF THE COMPANIES ACT AND PARAGRAPH 3.83(b) OF THE JSE LISTINGS REQUIREMENTS In accordance with section 122(3)(b) of the Companies Act, No. 71 of 2008 (“the Act”) and paragraph 3.83(b) of the JSE Listings Requirements, holders of ordinary shares in the Company are advised that the Public Investment Corporation SOC Limited (PIC) has formally notified the Company that it has increased its beneficial interest in the securities of the Company to 20.035% of the ordinary share capital of the Company, effective 31 October 2022. Aspen will file the notice with the Takeover Regulation Panel as required in terms of section 122(3)(a) of the Act. Durban 01 November 2022 Sponsor: Investec Bank Limited