ASPEN PHARMACARE HOLDINGS LIMITED (Incorporated in the Republic of South Africa) (“Aspen Holdings”) Registration number: 1985/002935/06 Share code: APN ISIN: ZAE000066692 LEI: 635400ZYSN1IRD5QWQ94 (“Aspen” or “the Company”) DEALING IN ASPEN SECURITIES BY A DIRECTOR, PRESCRIBED OFFICER, AND THE COMPANY SECRETARY OF THE COMPANY In compliance with the Listings Requirements of the JSE Limited, the following information is disclosed: Name : Sean Capazorio – Director Date of transaction : 28 October 2022 Nature of transaction : On market sale of securities* Number of securities : 3 303 Sale price : R 151.8276 Total value of transaction : R 501 486.56 Nature of interest in all transactions : Direct beneficial Class of securities : Ordinary shares Clearance obtained : Yes Name : Lorraine Angela Hill – Prescribed Officer Date of transaction : 28 October 2022 Nature of transaction : On market sale of securities* Number of securities : 4 735 Sale price : R 151.8276 Total value of transaction : R 718 903.69 Nature of interest in all transactions : Direct beneficial Class of securities : Ordinary shares Clearance obtained : Yes * Sold to cover tax commitments in terms of 2019 long-term incentive share awards that vested on 21 October 2022. Name : Riaan Verster – Company Secretary Date of transaction : 28 October 2022 Nature of transaction : On market sale of securities Number of securities : 3 015 Sale price : R 151.8276 Total value of transaction : R 457 760.21 Nature of interest in all transactions : Direct beneficial Class of securities : Ordinary shares Clearance obtained : Yes Durban 03 November 2022 Sponsor Investec Bank Limited